BE
Jupiler League
| Fri | 01-10-2021 | 20:45 | KV Mechelen | Standard Ličge |
| Sat | 02-10-2021 | 16:15 | KV Kortrijk | RSC Charleroi |
| Sat | 02-10-2021 | 18:30 | Cercle Brugge | Royale Union St |
| Sat | 02-10-2021 | 18:30 | Sint-Truidense | KV Oostende |
| Sat | 02-10-2021 | 20:45 | OH Leuven | Beerschot-Wilri |
| Sun | 03-10-2021 | 13:30 | RSC Anderlecht | Club Brugge |
| Sun | 03-10-2021 | 16:00 | RFC Seraing | SV Zulte Warege |
| Sun | 03-10-2021 | 18:30 | Antwerp | KAA Gent |
| Sun | 03-10-2021 | 21:00 | KAS Eupen | KRC Genk |
EN
Premier League
| Sat | 02-10-2021 | 13:30 | Manchester Unit | Everton |
| Sat | 02-10-2021 | 16:00 | Burnley | Norwich City |
| Sat | 02-10-2021 | 16:00 | Chelsea | Southampton |
| Sat | 02-10-2021 | 16:00 | Leeds | Watford |
| Sat | 02-10-2021 | 16:00 | Wolves | Newcastle Unite |
| Sat | 02-10-2021 | 18:30 | Brighton and Ho | Arsenal |
| Sun | 03-10-2021 | 15:00 | Crystal Palace | Leicester City |
| Sun | 03-10-2021 | 15:00 | Tottenham Hotsp | Aston Villa |
| Sun | 03-10-2021 | 15:00 | West Ham United | Brentford |
FR
Ligue 1
| Fri | 01-10-2021 | 21:00 | RC Lens | Stade Reims |
| Sat | 02-10-2021 | 17:00 | Montpellier HSC | Strasbourg |
| Sat | 02-10-2021 | 21:00 | OGC Nice | Stade Brest 29 |
| Sun | 03-10-2021 | 13:00 | Stade Rennais F | Paris Saint Ger |
| Sun | 03-10-2021 | 15:00 | Angers SCO | FC Metz |
| Sun | 03-10-2021 | 15:00 | FC Lorient | Clermont Foot |
| Sun | 03-10-2021 | 15:00 | AS Monaco | Girondins Borde |
| Sun | 03-10-2021 | 15:00 | FC Nantes | ESTAC Troyes |
| Sun | 03-10-2021 | 17:00 | Lille OSC | Olympique Marse |
GE
Bundesliga
| Fri | 01-10-2021 | 20:30 | 1.FC Köln | SpVgg Greuther |
| Sat | 02-10-2021 | 15:30 | Borussia Dortmu | FC Augsburg |
| Sat | 02-10-2021 | 15:30 | VfL Wolfsburg | Borussia Mönche |
| Sat | 02-10-2021 | 15:30 | VfB Stuttgart | TSG 1899 Hoffen |
| Sat | 02-10-2021 | 15:30 | Hertha BSC | SC Freiburg |
| Sat | 02-10-2021 | 18:30 | RB Leipzig | VfL Bochum |
| Sun | 03-10-2021 | 15:30 | 1.FSV Mainz 05 | 1.FC Union Berl |
| Sun | 03-10-2021 | 17:30 | Bayern München | Eintracht Frank |
| Sun | 03-10-2021 | 19:30 | Arminia Bielefe | Bayer Leverkuse |
IT
Serie A
| Fri | 01-10-2021 | 20:45 | Cagliari Calcio | Venezia |
| Sat | 02-10-2021 | 15:00 | Salernitana | Genoa CFC |
| Sat | 02-10-2021 | 18:00 | FC Torino | Juventus |
| Sat | 02-10-2021 | 20:45 | Sassuolo | Inter Milan |
| Sun | 03-10-2021 | 12:30 | Bologna FC | Lazio Roma |
| Sun | 03-10-2021 | 15:00 | Hellas Verona F | Spezia |
| Sun | 03-10-2021 | 15:00 | Sampdoria | Udinese Calcio |
| Sun | 03-10-2021 | 18:00 | Fiorentina ACF | Napoli |
| Sun | 03-10-2021 | 18:00 | AS Roma | Empoli FC |
NL
Eredivisie
| Fri | 01-10-2021 | 20:00 | FC Groningen | FC Twente |
| Sat | 02-10-2021 | 18:45 | RKC Waalwijk | Go Ahead Eagles |
| Sat | 02-10-2021 | 20:00 | Heracles Almelo | Willem II |
| Sat | 02-10-2021 | 20:00 | PEC Zwolle | SC Heerenveen |
| Sat | 02-10-2021 | 21:00 | Fortuna Sittard | NEC |
| Sun | 03-10-2021 | 14:30 | Ajax | FC Utrecht |
| Sun | 03-10-2021 | 14:30 | SC Cambuur | AZ |
| Sun | 03-10-2021 | 16:45 | Vitesse | Feyenoord |
| Sun | 03-10-2021 | 20:00 | PSV | Sparta Rotterda |
PO
Superliga
| Fri | 01-10-2021 | 20:00 | Maritimo | Moreirense FC |
| Fri | 01-10-2021 | 22:15 | FC Famalicăo | Vitória de Guim |
| Sat | 02-10-2021 | 16:30 | FC Vizela | Santa Clara |
| Sat | 02-10-2021 | 19:00 | FC Porto | Paços de Ferrei |
| Sat | 02-10-2021 | 21:30 | FC Arouca | Sporting Lisbon |
| Sun | 03-10-2021 | 16:30 | Belenenses CF | CD Tondela |
| Sun | 03-10-2021 | 19:00 | Benfica S.L. | Portimonense SC |
| Sun | 03-10-2021 | 19:00 | Estoril Praia G | Gil Vicente FC |
| Sun | 03-10-2021 | 21:30 | Sporting Braga | Boavista FC |
RU
Premier Liga 1
| Sat | 02-10-2021 | 12:00 | Rubin Kazan | Nizhny Novgorod |
| Sat | 02-10-2021 | 14:30 | Dynamo Moscow F | Krylya Sovetov |
| Sat | 02-10-2021 | 17:00 | CSKA Moscow | Krasnodar |
| Sat | 02-10-2021 | 17:00 | FK Arsenal Tula | Khimki |
| Sun | 03-10-2021 | 12:00 | Ufa | Ural |
| Sun | 03-10-2021 | 14:30 | Zenit St Peters | PFC Sochi |
| Sun | 03-10-2021 | 17:00 | Lokomotiv Moskv | FC Rostov |
| Sun | 03-10-2021 | 17:00 | Akhmat Grozny | FC Spartak Mosk |
| Fri | 15-10-2021 | 19:00 | FC Spartak Mosk | Dynamo Moscow F |
SC
Premier League
| Sat | 02-10-2021 | 16:00 | Aberdeen | Celtic FC |
| Sat | 02-10-2021 | 16:00 | Dundee United | Ross County FC |
| Sat | 02-10-2021 | 16:00 | Heart of Midlot | Motherwell FC |
| Sat | 02-10-2021 | 16:00 | Livingston | St Mirren |
| Sat | 02-10-2021 | 16:00 | Rangers FC | Hibernian FC |
| Sat | 02-10-2021 | 16:00 | St. Johnstone | Dundee FC |
| Sat | 16-10-2021 | 16:00 | Dundee FC | Aberdeen |
| Sat | 16-10-2021 | 16:00 | Hibernian FC | Dundee United |
| Sat | 16-10-2021 | 16:00 | Motherwell FC | Celtic FC |
SP
Primera Division
| Sun | 03-10-2021 | 18:30 | Athletic Bilbao | Deportivo Alavé |
| Sun | 03-10-2021 | 18:30 | Atletico Madrid | FC Barcelona |
| Sun | 03-10-2021 | 18:30 | CA Osasuna | Rayo Vallecano |
| Sun | 03-10-2021 | 18:30 | Espanyol de Bar | Real Madrid |
| Sun | 03-10-2021 | 18:30 | Cádiz CF | Valencia |
| Sun | 03-10-2021 | 18:30 | Elche CF | Celta de Vigo |
| Sun | 03-10-2021 | 18:30 | Getafe CF | Real Sociedad |
| Sun | 03-10-2021 | 18:30 | Granada CF | Sevilla FC |
| Sun | 03-10-2021 | 18:30 | Villarreal CF | Real Betis |
US
Major League
| Thu | 30-09-2021 | 01:00 | Toronto FC | FC Cincinnati |
| Thu | 30-09-2021 | 01:30 | CF Montreal | New England Rev |
| Thu | 30-09-2021 | 01:30 | New York Red Bu | Philadelphia Un |
| Thu | 30-09-2021 | 01:30 | Atlanta United | Inter Miami CF |
| Thu | 30-09-2021 | 02:00 | DC United | Minnesota Unite |
| Thu | 30-09-2021 | 02:00 | Chicago Fire | New York City F |
| Thu | 30-09-2021 | 02:00 | FC Dallas | Sporting Kansas |
| Thu | 30-09-2021 | 02:30 | Nashville SC | Orlando City SC |
| Thu | 30-09-2021 | 03:00 | Houston Dynamo | Vancouver White |
