BE
Jupiler League
| Fri | 03-12-2021 | 20:45 | Sint-Truidense | Royale Union St |
| Sat | 04-12-2021 | 16:15 | OH Leuven | KAA Gent |
| Sat | 04-12-2021 | 18:30 | KV Kortrijk | Cercle Brugge |
| Sat | 04-12-2021 | 18:30 | KV Oostende | KAS Eupen |
| Sat | 04-12-2021 | 20:45 | Club Brugge | RFC Seraing |
| Sun | 05-12-2021 | 13:30 | Beerschot-Wilri | Antwerp |
| Sun | 05-12-2021 | 16:00 | RSC Anderlecht | SV Zulte Warege |
| Sun | 05-12-2021 | 18:30 | Standard Ličge | RSC Charleroi |
| Sun | 05-12-2021 | 21:00 | KV Mechelen | KRC Genk |
EN
Premier League
| Thu | 02-12-2021 | 21:15 | Manchester Unit | Arsenal |
| Sat | 04-12-2021 | 13:30 | West Ham United | Chelsea |
| Sat | 04-12-2021 | 16:00 | Southampton | Brighton and Ho |
| Sat | 04-12-2021 | 16:00 | Newcastle Unite | Burnley |
| Sat | 04-12-2021 | 16:00 | Wolves | Liverpool |
| Sat | 04-12-2021 | 18:30 | Watford | Manchester City |
| Sun | 05-12-2021 | 15:00 | Leeds | Brentford |
| Sun | 05-12-2021 | 15:00 | Manchester Unit | Crystal Palace |
| Sun | 05-12-2021 | 15:00 | Tottenham Hotsp | Norwich City |
FR
Ligue 1
| Sat | 04-12-2021 | 17:00 | Olympique Marse | Stade Brest 29 |
| Sat | 04-12-2021 | 19:00 | Lille OSC | ESTAC Troyes |
| Sat | 04-12-2021 | 21:00 | RC Lens | Paris Saint Ger |
| Sun | 05-12-2021 | 13:00 | AS Saint-Étienn | Stade Rennais F |
| Sun | 05-12-2021 | 15:00 | FC Lorient | FC Nantes |
| Sun | 05-12-2021 | 15:00 | AS Monaco | FC Metz |
| Sun | 05-12-2021 | 15:00 | Montpellier HSC | Clermont Foot |
| Sun | 05-12-2021 | 15:00 | Stade Reims | Angers SCO |
| Sun | 05-12-2021 | 17:00 | OGC Nice | Strasbourg |
GE
Bundesliga
| Fri | 03-12-2021 | 20:30 | 1.FC Union Berl | RB Leipzig |
| Sat | 04-12-2021 | 15:30 | Bayer Leverkuse | SpVgg Greuther |
| Sat | 04-12-2021 | 15:30 | TSG 1899 Hoffen | Eintracht Frank |
| Sat | 04-12-2021 | 15:30 | 1.FSV Mainz 05 | VfL Wolfsburg |
| Sat | 04-12-2021 | 15:30 | FC Augsburg | VfL Bochum |
| Sat | 04-12-2021 | 15:30 | Arminia Bielefe | 1.FC Köln |
| Sat | 04-12-2021 | 18:30 | Borussia Dortmu | Bayern München |
| Sun | 05-12-2021 | 15:30 | VfB Stuttgart | Hertha BSC |
| Sun | 05-12-2021 | 17:30 | Borussia Mönche | SC Freiburg |
IT
Serie A
| Sat | 04-12-2021 | 15:00 | AC Milan | Salernitana |
| Sat | 04-12-2021 | 18:00 | AS Roma | Inter Milan |
| Sat | 04-12-2021 | 20:45 | Napoli | Atalanta Bergam |
| Sun | 05-12-2021 | 12:30 | Bologna FC | Fiorentina ACF |
| Sun | 05-12-2021 | 15:00 | Spezia | Sassuolo |
| Sun | 05-12-2021 | 15:00 | Venezia | Hellas Verona F |
| Sun | 05-12-2021 | 18:00 | Sampdoria | Lazio Roma |
| Sun | 05-12-2021 | 20:45 | Juventus | Genoa CFC |
| Mon | 06-12-2021 | 18:30 | Empoli FC | Udinese Calcio |
NL
Eredivisie
| Fri | 03-12-2021 | 20:00 | FC Groningen | PEC Zwolle |
| Sat | 04-12-2021 | 16:30 | PSV | FC Utrecht |
| Sat | 04-12-2021 | 18:45 | SC Cambuur | Vitesse |
| Sat | 04-12-2021 | 21:00 | Heracles Almelo | SC Heerenveen |
| Sun | 05-12-2021 | 12:15 | RKC Waalwijk | NEC |
| Sun | 05-12-2021 | 14:30 | AZ | Sparta Rotterda |
| Sun | 05-12-2021 | 14:30 | Go Ahead Eagles | FC Twente |
| Sun | 05-12-2021 | 16:45 | Feyenoord | Fortuna Sittard |
| Fri | 10-12-2021 | 20:00 | Willem II | SC Cambuur |
PO
Superliga
| Fri | 03-12-2021 | 20:00 | Portimonense SC | FC Porto |
| Fri | 03-12-2021 | 22:15 | Benfica S.L. | Sporting Lisbon |
| Sat | 04-12-2021 | 16:30 | CD Tondela | Moreirense FC |
| Sat | 04-12-2021 | 19:00 | Boavista FC | Maritimo |
| Sat | 04-12-2021 | 21:30 | Paços de Ferrei | Vitória de Guim |
| Sun | 05-12-2021 | 16:30 | Santa Clara | FC Arouca |
| Sun | 05-12-2021 | 19:00 | Gil Vicente FC | FC Famalicăo |
| Sun | 05-12-2021 | 21:30 | Sporting Braga | Estoril Praia G |
| Mon | 06-12-2021 | 21:15 | FC Vizela | Belenenses CF |
RU
Premier Liga 1
| Fri | 03-12-2021 | 18:00 | Zenit St Peters | FC Rostov |
| Fri | 03-12-2021 | 18:00 | FC Spartak Mosk | Akhmat Grozny |
| Fri | 03-12-2021 | 18:00 | Krylya Sovetov | CSKA Moscow |
| Fri | 03-12-2021 | 18:00 | Dynamo Moscow F | Ufa |
| Fri | 03-12-2021 | 18:00 | Lokomotiv Moskv | Ural |
| Fri | 03-12-2021 | 18:00 | PFC Sochi | Krasnodar |
| Fri | 03-12-2021 | 18:00 | Nizhny Novgorod | Rubin Kazan |
| Fri | 03-12-2021 | 18:00 | Khimki | FK Arsenal Tula |
| Fri | 10-12-2021 | 18:00 | FC Rostov | Ural |
SC
Premier League
| Sat | 04-12-2021 | 16:00 | Aberdeen | St Mirren |
| Sat | 04-12-2021 | 16:00 | Dundee United | Celtic FC |
| Sat | 04-12-2021 | 16:00 | Hibernian FC | Motherwell FC |
| Sat | 04-12-2021 | 16:00 | Livingston | Heart of Midlot |
| Sat | 04-12-2021 | 16:00 | Rangers FC | Dundee FC |
| Sat | 04-12-2021 | 16:00 | St. Johnstone | Ross County FC |
| Sat | 11-12-2021 | 16:00 | Celtic FC | Motherwell FC |
| Sat | 11-12-2021 | 16:00 | Dundee United | Livingston |
| Sat | 11-12-2021 | 16:00 | Heart of Midlot | Rangers FC |
SP
Primera Division
| Fri | 03-12-2021 | 21:00 | Granada CF | Deportivo Alavé |
| Sat | 04-12-2021 | 14:00 | Sevilla FC | Villarreal CF |
| Sat | 04-12-2021 | 16:15 | FC Barcelona | Real Betis |
| Sat | 04-12-2021 | 18:30 | Atletico Madrid | Real Club Depor |
| Sat | 04-12-2021 | 21:00 | Real Sociedad | Real Madrid |
| Sun | 05-12-2021 | 14:00 | Rayo Vallecano | Espanyol de Bar |
| Sun | 05-12-2021 | 16:15 | Elche CF | Cádiz CF |
| Sun | 05-12-2021 | 18:30 | Levante UD | CA Osasuna |
| Sun | 05-12-2021 | 21:00 | Celta de Vigo | Valencia |
US
Major League
| Mon | 08-11-2021 | Sporting Kansas | Real Salt Lake | 0 - 1 |
| Mon | 08-11-2021 | Colorado Rapids | Los Angeles FC | 5 - 2 |
| Mon | 08-11-2021 | LA Galaxy | Minnesota Unite | 3 - 3 |
| Mon | 08-11-2021 | San Jose Earthq | FC Dallas | 1 - 1 |
| Mon | 08-11-2021 | Portland Timber | Austin FC | 3 - 0 |
| Mon | 08-11-2021 | Vancouver White | Seattle Sounder | 1 - 1 |
| Sun | 07-11-2021 | New England Rev | Inter Miami CF | 0 - 1 |
| Sun | 07-11-2021 | CF Montreal | Orlando City SC | 0 - 2 |
| Sun | 07-11-2021 | New York City F | Philadelphia Un | 1 - 1 |
